Bryan McDonald

Atlas-guided discovery of transcription factors for T cell programming

Chung HK, Liu C, Battu A, … McDonald B, … Milner JJ, Kaech SM, Wang W

Nature 2026 651(8107):1077–1087

Early chromatin remodeling events in acutely stimulated CD8⁺ T cells

McDonald B, Chick BY, Hargreaves DC, Kaech SM

Yale Journal of Biology and Medicine 2023 96(4):467–473

Canonical BAF complex activity shapes the enhancer landscape that licenses CD8⁺ T cell effector and memory fates

McDonald B, Chick BY, Ahmed NS, Burns M, Ma S, Casillas E, Chen D, Mann TH, O'Connor C, Hah N, Hargreaves DC, Kaech SM

Immunity 2023 56(6):1303–1319.e5

Fc-optimized anti-CCR8 antibody depletes regulatory T cells in human tumor models

Campbell JR*, McDonald BR*, Mesko PB, Siemers NO, Singh PB, … Jain R, Lan RY

Cancer Research 2021 81(11):2983–2994 * Co-first authors

The architectural design of CD8⁺ T cell responses in acute and chronic infection: parallel structures with divergent fates

Chung HK, McDonald B, Kaech SM

Journal of Experimental Medicine 2021 218(4):e20201730 Review

Heterogenous populations of tissue-resident CD8⁺ T cells are generated in response to infection and malignancy

Milner JJ, Toma C, He Z, Kurd NS, Nguyen QP, McDonald B, … Chang JT, Omilusik KD, Goldrath AW

Immunity 2020 52(5):808–824.e7

cGAS-STING signaling regulates initial innate control of cytomegalovirus infection

Lio CW, McDonald B, Takahashi M, Dhanwani R, Sharma N, Huang J, Pham E, Benedict CA, Sharma S

Journal of Virology 2016 90(17):7789–7797